SIMPONI® injection schedule for UC1


Week 0: 2 (100-mg) injections

SmartJect® autoinjector

SmartJect® autoinjector

Week 2: 1 (100-mg) injection

SmartJect® autoinjector


Week 6 and every 4 weeks thereafter:
1 (100-mg) injection

SmartJect® autoinjector

Each 100-mg single-dose SmartJect® autoinjector contains a prefilled glass syringe providing 100 mg of SIMPONI® per 1 mL of solution. Also available in a 100-mg prefilled syringe.

SIMPONI® is intended for use under the guidance and supervision of a physician. Patients may self-inject SIMPONI® after physician approval and proper training.

Prior to initiating SIMPONI® and periodically during therapy, patients should be evaluated for active tuberculosis and tested for latent infection. Prior to initiating SIMPONI®, patients should be tested for hepatitis B viral infection.


• SIMPONI® uses an L-histidine-based injection buffer1

SmartJect® autoinjector training video

This video demonstrates the necessary steps you can take to help properly teach your patients to inject their SIMPONI® using the SmartJect® autoinjector.

Reference: 1. SIMPONI® (golimumab) Prescribing Information. Janssen Biotech, Inc.